The Right Bacteria for Newborn Foals

Newborn mammals are born with an essentially sterile gut, and begin acquiring gut microbes during the birthing process. Mammalian milk is known to contain complex sugars that strongly influence the type of bacteria that colonize the newborn gut, but the details of this process in foals has not been clear until now. This recent study by Dr. Karav and colleagues provides the most detailed analysis of mare milk oligosaccharides available to date. These data allowed Evolve to select the most targeted bacterial strains known to thrive in the presence of mare milk, B. infantis and L. plantarum, to create GlycoGuard®, the first clinically proven probiotic to stably colonize the foal intestine. GlycoGuard can help give vulnerable nursing foals the intestinal support they need for a great start in life. 

AAEP 2017: GlycoGuard Supports Intestinal Health in Nursing Foals

At AAEP 2017, Dr. Steve Frese (Evolve BioSystems, Inc.) shares the scientific background and exciting clinical results of providing GlycoGuard to newborn foals during a presumed C. difficile outbreak. GlycoGuard is the leading oral microbial gel specifically designed for use in nursing foals to support intestinal health.

  • The Problem : C. diff outbreak in newborn foals (00:00-4:43
  • Designing the Solution: Mare’s milk and the foal gut microbiome ( Jump to: 4:44-8:28
  • Putting GlycoGuard to the Test: Study results following foal probiotic administration ( Jump: 8:29-14:02
  • Conclusions and Discussion: Use of GlycoGuard in practice and future clinical studies ( Jump to: 14:03-18:45

The Milk Microbiome Connection

By: Tracy Shafizadeh, PhD
Director of Scientific Communications, Evolve BioSystems

As microbiome research and development continues to grow, a specific focus on establishing the newborn gut microbiome may be key to long term health across various mammalian species.